《英文msh詞典》HIV 1 Envelope Protein gp120
[入口詞] HIV 1 Envelope Protein gp120
[主題詞] HIV Envelope Protein gp120
[英文釋義] External envelope protein of the human immunodeficiency virus which is encoded by the HIV env gene. It has a molecular weight of 120 kD and contains numerous glycosylation sites. Gp120 binds to cells expressing CD4 cell-surface antigens,most notably T4-lymphocytes and monocytes/macrophages. Gp120 has been shown to interfere with the normal function of CD4 and is at least partly responsible for the cytopathic effect of HIV.